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THE CHRONIC DISEASE RESEARCH FOUNDATION

Registered charity 1186102 · accounts filings on the Charity Commission register · also known as CDRF

The CDRF, an independent medical research charity, funds a range of research programs that aim to discover the cause of common chronic diseases such as heart disease, arthritis, migraine, asthma, dementia. The CDRF runs many projects at the Department of Twin Research, St Thomas' Hospital. It is hoped the research will contribute to the development of future diagnostic tests and treatments.

Causes: Education/training · The Advancement Of Health Or Saving Of Lives · Grant history (this charity is a funder) · website · Get email alerts

Latest income
£214k
Latest spending
£947k
Registered
2019
Accounts read
FY2025

Financial health, per its FY2025 accounts

The accounts state that the charity reported a deficit of £732,638 for the year ended 5 April 2025, resulting in closing net assets of £5,112,615. The trustees' report confirms that unrestricted funds of £543,110 remain well above the stated policy minimum of approximately six months' projected management and administrative expenditure. The independent auditors confirmed that the use of the going concern basis of accounting is appropriate with no material uncertainties identified.

Automated summary of the FY2025 accounts; the evidenced findings below carry the verbatim passages.

What the accounts disclose

Largest income source: none
“The Foundation’s primary income source is donations and bequests. For general purposes, the Foundation raised £1,101 (2024: £445) in donations from private donors and investment income of £62,542 (2024: £178,915).” — page 5
Per its FY2025 accounts as filed with the Charity Commission.
Reserves policy: approximately six months’ projected management and administrative expenditure (held: £543k)
“The trustees’ policy regarding free reserves is to set a minimum for such reserves equal to approximately six months’ projected management and administrative expenditure.” — page 5
Per its FY2025 accounts as filed with the Charity Commission.
Related-party transaction: Collyer Bristow LLP, a firm where Trustee Mr M D B Simon is a partner, was charged £9,000 for administration and other legal services.
“During the year, £9,000 (2024: £2,880) was charged by Collyer Bristow for administration and other legal services. Mr M D B Simon, Trustee, is a partner of Collyer Bristow.” — page 26
“Expenditure in the year includes £234,225 (2024: £189,669) to projects of which Professor Tim Spector (Medical Director) is the lead researcher. A further £158,493 (2024: £1,035,248) has been approved for payment to projects led by Professor Spector.” — page 26
Per its FY2025 accounts as filed with the Charity Commission.
Related-party transaction: Expenditure of £234,225 was incurred on projects led by Medical Director Professor Tim Spector, with a further £158,493 approved for payment to his projects.
“During the year, £9,000 (2024: £2,880) was charged by Collyer Bristow for administration and other legal services. Mr M D B Simon, Trustee, is a partner of Collyer Bristow.” — page 26
“Expenditure in the year includes £234,225 (2024: £189,669) to projects of which Professor Tim Spector (Medical Director) is the lead researcher. A further £158,493 (2024: £1,035,248) has been approved for payment to projects led by Professor Spector.” — page 26
Per its FY2025 accounts as filed with the Charity Commission.
Related-party transaction: The Foundation holds an option to buy shares in Zoe Limited, founded by Medical Director Professor Tim Spector, valued at no more than £4,900.
“During the year, £9,000 (2024: £2,880) was charged by Collyer Bristow for administration and other legal services. Mr M D B Simon, Trustee, is a partner of Collyer Bristow.” — page 26
“Expenditure in the year includes £234,225 (2024: £189,669) to projects of which Professor Tim Spector (Medical Director) is the lead researcher. A further £158,493 (2024: £1,035,248) has been approved for payment to projects led by Professor Spector.” — page 26
Per its FY2025 accounts as filed with the Charity Commission.

Accounts audited by Bourner Bullock. Discloses 5 of 6 completeness components.

Corporate structure

Public fundraising profile: JustGiving — CDRF (matched by registered charity number).

Company officers (Companies House)

Current officers of the charity’s own company per the Companies House register, cross-checked against the Charity Commission trustee list by name. A director not on the trustee list is usually a timing or naming difference between the two registers — check both records before drawing conclusions.

Official officers record.

Public profiles (found on the charity’s own website): instagram

Structured financials (annual return, FY ending 05/04/2024)

Total income
£4.4m
Total spending
£1.4m
Cost of raising funds
£6k
Reserves (reported)
£633k
Employees
1

Reported reserves equal ~5.5 months of spending — below the median for charities its size (median 7.0 months; benchmarks).

Per its annual return, largest income source: Donations and legacies (96% of income) — components as reported reconcile to the return’s total income; not from the accounts narrative.

Per its annual return, cost of raising funds: 0.1% of total income — below the median for charities its size (2.9%) (benchmarks).

Register events

Trustees · trustee networks

Trustee list from the Charity Commission register (current, not historical).

Operates in: Throughout London

Income and spending

Financial year endIncomeSpending
05/04/2025£214k£947k
05/04/2024£4.4m£1.4m
05/04/2023£791k£1.4m
05/04/2022£481k£1.8m
05/04/2021£3.2m£690k

Common questions

Is THE CHRONIC DISEASE RESEARCH FOUNDATION financially healthy?

Per its FY2025 accounts: The accounts state that the charity reported a deficit of £732,638 for the year ended 5 April 2025, resulting in closing net assets of £5,112,615. The trustees' report confirms that unrestricted funds of £543,110 remain well above the stated policy minimum of approximately six months' projected management and administrative expenditure. The independent auditors confirmed that the use of the going concern basis of accounting is appropriate with no material uncertainties identified. Its FY2025 accounts were audited by Bourner Bullock.

Who funds THE CHRONIC DISEASE RESEARCH FOUNDATION?

Funders whose own accounts filings name THE CHRONIC DISEASE RESEARCH FOUNDATION as a grant recipient include DENISE COATES FOUNDATION.

Known funders

Grants to this charity found in funders’ own accounts filings.

FunderYearAmountPurpose (as stated by the funder)
DENISE COATES FOUNDATIONFY2024£4.2mTo fund a 5-year Ageing Research project and to fund pilot projects, offering fellowships to appropriate candidates whilst supporting PhD students and related p
DENISE COATES FOUNDATIONFY2023£758kFund the Ageing Research 5 year project and support activities related to the study of the Microbiome and ageing.

Funders of similar charities

Funders whose accounts show grants to charities similar to this one (and no recorded grant to this charity) — a starting list for fundraisers.

FunderSimilar charities fundedAmount to them
ROBERT LUFF FOUNDATION LIMITED2£92k
SUSANNA PEAKE CHARITABLE TRUST2£14k
THE OAKDALE TRUST2£6k
CHAPMAN CHARITABLE TRUST2£3k
WELLCOME TRUST1£142.6m
THE CHRIS BANTON FOUNDATION1£5.5m
BRITISH HEART FOUNDATION1£3.2m
THE ALDAMA FOUNDATION1£565k

Charities like this

Semantically similar by activities and financial character, from our analysed corpus. Compare with PAIN RELIEF FOUNDATION.

Side by side with its peers

CharityIncomeTop pay bandStaff >£60kReserves vs policyFundraising costGoing concern
THE CHRONIC DISEASE RESEARCH FOUNDATION£214k—0above—no doubt
PAIN RELIEF FOUNDATION FY2026£333k—0unclear—no doubt
THE FRANCIS CRICK INSTITUTE LIMITED FY2025£246.2m—337above—no doubt
THE LORNA AND YUTI CHERNAJOVSKY BIOMEDICAL RESEARCH FOUNDATION FY2025£508k—0above—no doubt
THE WILLIAM HARVEY RESEARCH FOUNDATION FY2025£2.4m—0unclear—no doubt
THE ORTHOPAEDIC INSTITUTE LIMITED FY2025£319k—0unclear—no doubt

Each row is that charity’s latest analysed filing; every value is quote-backed on its own page.