THE FRANCIS CRICK INSTITUTE LIMITED

Registered charity 1140062 · accounts filings on the Charity Commission register · also known as THE FRANCIS CRICK INSTITUTE, UKCMRI, UKCMRI (UNITED KINGDOM CENTRE FOR MEDICAL RESEARCH AND INNOVATION), UKCMRI LIMITED

The Francis Crick Institute is dedicated to understanding the fundamental biology underlying health and disease. Our work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections and neurodegenerative diseases.

Causes: Education/training · The Advancement Of Health Or Saving Of Lives · Arts/culture/heritage/science · website · Get email alerts

Latest income
£246.2m
Latest spending
£254.9m
Registered
2011
Accounts read
FY2025

Financial health, per its FY2025 accounts

The accounts state that the charity reported a net deficit of £8.6m for the year ended 31 March 2025, with total income of £246.2m and total expenditure of £254.9m. Per the trustees' report, total reserves of £66.3m exceed the stated policy target of £35m, providing a buffer against inflationary pressures. The trustees confirm adequate resources to continue in operational existence for the foreseeable future.

Automated summary of the FY2025 accounts; the evidenced findings below carry the verbatim passages.

What the accounts disclose

Employees paid over £60,000: 337
“The number of employees whose emoluments, excluding pension contributions and employer’s national insurance but including benefits in kind, were in excess of £60,000 was:” — page 59
Per its FY2025 accounts as filed with the Charity Commission.
Largest income source: Core funding from founding shareholders (58% of income)
“58% of this derived from core funding which grew by a planned £2.5m in the year.” — page 25
Per its FY2025 accounts as filed with the Charity Commission.
Reserves policy: three months' core funding income, including a minimum of £10m in cash or immediately accessible investment funds (held: £66.3m)
“the trustees believe that the charity should have access to minimum reserves equivalent to three months’ core funding income, including a minimum of £10m in cash or immediately accessible investment funds. This equated to a target of £35m at 31 March 2025”
Per its FY2025 accounts as filed with the Charity Commission.
Related-party transaction: Seconded staff from university partners (Imperial, UCL, King's) and Cancer Research UK provided at nil cost.
“Research lab staff have been seconded to the Crick at nil cost, a gift in kind of £1,222k (2024: £1,148k) has been recognised for these services.”
“During the year the Crick invested £1,939k into Enara Bio and received 5,239,442 series B-1 preference shares. The trustee was not involved in either of the investment decisions.”
Per its FY2025 accounts as filed with the Charity Commission.
Related-party transaction: Investment in Enara Bio, a spin-out where trustee Dame Kate Bingham is a director.
“Research lab staff have been seconded to the Crick at nil cost, a gift in kind of £1,222k (2024: £1,148k) has been recognised for these services.”
“During the year the Crick invested £1,939k into Enara Bio and received 5,239,442 series B-1 preference shares. The trustee was not involved in either of the investment decisions.”
Per its FY2025 accounts as filed with the Charity Commission.
Related-party transaction: Trustees donated £1,225k to the charity.
“Research lab staff have been seconded to the Crick at nil cost, a gift in kind of £1,222k (2024: £1,148k) has been recognised for these services.”
“During the year the Crick invested £1,939k into Enara Bio and received 5,239,442 series B-1 preference shares. The trustee was not involved in either of the investment decisions.”
Per its FY2025 accounts as filed with the Charity Commission.

Accounts audited by BDO LLP. Discloses 5 of 6 completeness components.

Public fundraising profile: JustGiving — The Francis Crick Institute (matched by registered charity number).

Property (HM Land Registry)

1 registered title in England and Wales held by the charity’s company or corporate body (0 freehold). All charity-held property. Contains HM Land Registry data © Crown copyright, OGL v3.0.

Structured financials (annual return, FY ending 31/03/2025)

Total income
£246.2m
Total spending
£254.9m
Cost of raising funds
£1.6m
Reserves (reported)
£66.3m
Employees
1,458

Reported reserves equal ~3.1 months of spending — above the median for charities its size (median 2.7 months; benchmarks).

Per its annual return, largest income source: Donations and legacies (91% of income) — components as reported reconcile to the return’s total income; not from the accounts narrative.

Per its annual return, cost of raising funds: 0.6% of total income — below the median for charities its size (2.9%) (benchmarks).

Trustees · trustee networks

Trustee list from the Charity Commission register (current, not historical).

Operates in: Throughout England And Wales

Income and spending

Financial year endIncomeSpending
31/03/2025£246.2m£254.9m
31/03/2024£231.2m£237.6m
31/03/2023£213.2m£210.3m
31/03/2022£185.6m£197.4m
31/03/2021£174.9m£188.0m

Common questions

Is THE FRANCIS CRICK INSTITUTE LIMITED financially healthy?

Per its FY2025 accounts: The accounts state that the charity reported a net deficit of £8.6m for the year ended 31 March 2025, with total income of £246.2m and total expenditure of £254.9m. Per the trustees' report, total reserves of £66.3m exceed the stated policy target of £35m, providing a buffer against inflationary pressures. The trustees confirm adequate resources to continue in operational existence for the foreseeable future. Its FY2025 accounts were audited by BDO LLP.

Who funds THE FRANCIS CRICK INSTITUTE LIMITED?

Funders whose own accounts filings name THE FRANCIS CRICK INSTITUTE LIMITED as a grant recipient include WELLCOME TRUST, BRITISH HEART FOUNDATION, THE CHRIS BANTON FOUNDATION, Blood Cancer UK Research, THE ALDAMA FOUNDATION.

Known funders

Grants to this charity found in funders’ own accounts filings.

FunderYearAmountPurpose (as stated by the funder)
WELLCOME TRUSTFY2022£142.6m
BRITISH HEART FOUNDATIONFY2025£3.2mResearch
THE CHRIS BANTON FOUNDATIONFY2023£2.5m
THE CHRIS BANTON FOUNDATIONFY2024£2.5m
THE CHRIS BANTON FOUNDATIONFY2025£500k
Blood Cancer UK ResearchFY2022£379kResearch
THE ALDAMA FOUNDATIONFY2024£325kAdvancement of health or the saving of lives
THE STONEYGATE TRUSTFY2024£318k
THE LISTER INSTITUTE OF PREVENTIVE MEDICINEFY2021£250kLister Prize Fellowship for Dr James Lee
THE ALDAMA FOUNDATIONFY2022£240kAdvancement of health or the saving of lives
THE ROYAL SOCIETY OF LONDON FOR IMPROVING NATURAL KNOWLEDGE (COMMONLY KNOWN AS THE ROYAL SOCIETY)FY2023£188kGrants to institutions
THE M AND L CHARITABLE TRUSTFY2025£180k
ROSETREESFY2023£130k
THE WOOSNAM FOUNDATIONFY2022£120k
THE HOBSON CHARITY LIMITEDFY2025£100kMedical
PROSTATE CANCER RESEARCHFY2022£86kTargeting Wnt Signalling
THE NINEVEH CHARITABLE TRUSTFY2022£80k
THE WOOSNAM FOUNDATIONFY2023£50kThe advancement of research and education
Vivensa FoundationFY2022£49kHeterogeneity of Plasma Cells and of its Survival Niche in the context of Ageing
PROSTATE CANCER RESEARCHFY2023£48kPTEN and TSGs
THE STONEYGATE TRUSTFY2023£32k
THE STONEYGATE TRUSTFY2025£21k
THE HARRISON-FRANK FAMILY FOUNDATION (UK) LIMITEDFY2024£20k
THE COMPANY OF BIOLOGISTSFY2025£15kMultiple grants (see Note 7 detail)
MEDICAL RESEARCH FOUNDATIONFY2025£12kThird Developmental Biology Symposium
THE COMPANY OF BIOLOGISTSFY2023£11kOther grants
THE BRITISH SOCIETY FOR HAEMATOLOGYFY2025£10kResearch grants
MEDICAL RESEARCH FOUNDATIONFY2025£9kCrick summer student training programme
MEDICAL RESEARCH FOUNDATIONFY2025£9kCollaboration with Professor Carlos Estella to develop genetic tools in cell proliferation and cell death
Adelphi Genetics ForumFY2025£1kHAAM Summer School 2025 - virtual
WELLCOME TRUSTFY2025£19Discovery Research
WELLCOME TRUSTFY2025£19Wellcome Leap
ROSETREESFY2024£0

Government & lottery funding

Grants to this charity published as open data by government and lottery funders (360Giving).

FunderDateAmountPurpose
UK government21/12/2023£25kEstablishing The Immune Potential Of Enteric Glial Cells
UK government06/09/2023£127k: Next-generation models and genetic therapies for rare neuromuscular diseases
UK government14/08/2023£75kThe metabolism of breast cancer metastasis to the lung: Key pathways and their implications in the metastatic microenvironment.
UK government04/05/2023£39kOpen Access Block Award 2023 - The Francis Crick Institute
UK government27/04/2023£272kBiological validation of human liver somatic mutations
UK government04/04/2023£131kGastruloGO: From gastruloid to gonadoid: exploring germ cell development in an embryo-like system
UK government10/03/2023£675kDeveloping a rule book for rational discovery of molecular glues for intractable targets
UK government31/01/2023£97kNetwork mechanisms underlying multisensory spatial attention
UK government12/12/2022£237kThe Role of Serotonin in the Modulation of Multisensory Spatial Attention
UK government27/09/2022£263kSIGMA: Small molecule Inhibitors targeting the Genetic determinants of Mutagenesis and Adaptability in Mycobacterium tuberculosis
UK government08/09/2022£51kMultidimensional investigation of cellular dynamics and lineage relationships in the vertebrate neural tube
UK government06/09/2022£138kDiscovery of High-level Antibiotic Resistance Mechanisms in Nature.
UK government23/08/2022£385kChromosome end protection in stem cells and development
UK government22/08/2022£345kWIME: WNT-mediated immune evasion in intestinal homeostasis, regeneration and cancer
UK government12/08/2022£102kImmuneMetTx
UK government04/07/2022£259kCRYPTOEXPORT: Exploring virulence and effector export in the intestinal parasite Cryptosporidium
UK government04/07/2022£259kMultiSensDepthPercep: Midbrain Circuits Underlying Multisensory Depth Perception
UK government04/07/2022£259kCancerNeuroscience: Systematic dissection of the crosstalk between cancer and the nervous system
UK government04/07/2022£259kFoldingMap: Resolving Protein Biogenesis Pathways
UK government29/06/2022£163kImpact of Ageing on Humoral Immune Protection from Infection
UK government25/05/2022£244kBiophysical and Structural Analysis of Recombination Repair Proteins
UK government25/04/2022£340kA Nanopathology Platform for Prediction and Early Detection of Disease in Kidney Transplant Rejection
UK government11/04/2022£214kCrosstalk Between Tumour and Draining Lymph Nodes and its Impact on Triple-Negative Breast Cancer
UK government16/03/2022£497kMRC IAA 2021 The Francis Crick Institute
UK government04/02/2022£595kIntegration of functional and structural knowledge across scales to decipher information processing in the mammalian brain

Funders of similar charities

Funders whose accounts show grants to charities similar to this one (and no recorded grant to this charity) — a starting list for fundraisers.

Charities like this

Semantically similar by activities and financial character, from our analysed corpus. Compare with THE CHRONIC DISEASE RESEARCH FOUNDATION.

Side by side with its peers

CharityIncomeTop pay bandStaff >£60kReserves vs policyFundraising costGoing concern
THE FRANCIS CRICK INSTITUTE LIMITED£246.2m—337above—no doubt
THE CHRONIC DISEASE RESEARCH FOUNDATION FY2025£214k—0above—no doubt
THE INSTITUTE FOR CANCER VACCINES AND IMMUNOTHERAPY FY2025£433k£70,001 - £80,0001unclear6.0%no doubt
CANCER RESEARCH WALES FY2026£5.9m——unclear—no doubt
CRIS CANCER FOUNDATION FY2025£3.8mmore than £60,0001unclear—no doubt
THE LISTER INSTITUTE OF PREVENTIVE MEDICINE FY2025£694k—0unclear—no doubt

Each row is that charity’s latest analysed filing; every value is quote-backed on its own page.