THE FRANCIS CRICK INSTITUTE LIMITED
The Francis Crick Institute is dedicated to understanding the fundamental biology underlying health and disease. Our work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections and neurodegenerative diseases.
Objects
THE ADVANCEMENT OF HUMAN HEALTH AND EDUCATION FOR THE BENEFIT OF THE PUBLIC BY THE PROMOTION AND CARRYING OUT, DIRECTLY OR INDIRECTLY, OF ALL ASPECTS OF BIOMEDICAL RESEARCH AND INNOVATION, WHICH SHALL INCLUDE IN PARTICULAR THE FOLLOWING:1 ESTABLISHING, OPERATING AND MANAGING A CENTRE FOR MEDICAL RESEARCH AND INNOVATION;2 ENGAGING IN, ENCOURAGING AND SUPPORTING:2.1 RESEARCH INTO ANY OF THE BIOSCIENCES; 2.2 THE DISCOVERY, INVENTION, IMPROVEMENT, DEVELOPMENT AND APPLICATION OF PREVENTIONS, TREATMENTS, CURES, DIAGNOSTICS AND OTHER MEDICAL AGENTS, METHODS AND PROCESSES THAT MAY IN ANY WAY PREVENT OR RELIEVE ILLNESS, DISEASE, DISABILITY OR DISORDERS OF WHATEVER NATURE (INCLUDING, WITHOUT LIMITATION, ALL FORMS OF CANCER); AND 3 DEVELOPING AND TRAINING SCIENTISTS AND SUPPORTING BIOMEDICAL RESEARCH ENDEAVOURS.
Financial health, per its FY2025 accounts
The accounts state that the charity reported a net deficit of £8.6m for the year ended 31 March 2025, driven by a £17.2m increase in expenditure that outpaced a £15.0m rise in income. Despite this operational loss, the charity maintains total reserves of £66.3m, which significantly exceed its stated policy target of £35m, providing a buffer against inflationary pressures. The trustees confirm that the charity has adequate resources to continue in operational existence for the foreseeable future.
What the accounts disclose
“58% of this derived from core funding which grew by a planned £2.5m in the year.” — page 25
“the trustees believe that the charity should have access to minimum reserves equivalent to three months’ core funding income, including a minimum of £10m in cash or immediately accessible investment funds.”
“Income received included £60,626k (2024: £60,500k) core funding and £3,921k (2024: £1,041k) research grant funding and other income.”
“Research lab staff have been seconded to the Crick at nil cost, a gift in kind of £2,641k (2024: £3,154k) has been recognised for these services.”
“Income received included £60,626k (2024: £60,500k) core funding and £3,921k (2024: £1,041k) research grant funding and other income.”
“Research lab staff have been seconded to the Crick at nil cost, a gift in kind of £2,641k (2024: £3,154k) has been recognised for these services.”
“Income received included £60,626k (2024: £60,500k) core funding and £3,921k (2024: £1,041k) research grant funding and other income.”
“Research lab staff have been seconded to the Crick at nil cost, a gift in kind of £2,641k (2024: £3,154k) has been recognised for these services.”
“Income received included £60,626k (2024: £60,500k) core funding and £3,921k (2024: £1,041k) research grant funding and other income.”
“Research lab staff have been seconded to the Crick at nil cost, a gift in kind of £2,641k (2024: £3,154k) has been recognised for these services.”
“Income received included £60,626k (2024: £60,500k) core funding and £3,921k (2024: £1,041k) research grant funding and other income.”
“Research lab staff have been seconded to the Crick at nil cost, a gift in kind of £2,641k (2024: £3,154k) has been recognised for these services.”
Policies the charity declares
- Bullying and harassment policy and procedures
- Conflicting interests
- Engaging external speakers at charity events policy and procedures
- Financial reserves policy and procedures
- Internal charity financial controls policy and procedures
- Internal risk management policy and procedures
- Investing charity funds policy and procedures
- Investment
- Paying staff
- Risk management
- Safeguarding policy and procedures
- Safeguarding vulnerable beneficiaries
- Serious incident reporting policy and procedures
- Trustee conflicts of interest policy and procedures
- Trustee expenses policy and procedures
From the charity’s annual return (Part A, self-declared)
Self-declared on the annual return for the financial year ending 31/03/2025
- Government income: £377,891 — grants £377,891 (2); under 1% of the £246,171,125 total gross income on the same return
- Employees paid over £60,000: 337 (£60,001–£70,000: 141; £70,001–£80,000: 50; £80,001–£90,000: 33; £90,001–£100,000: 36; £100,001–£110,000: 18; £110,001–£120,000: 8; £120,001–£130,000: 7; £130,001–£140,000: 7; £140,001–£150,000: 4; £150,001–£200,000: 18; £200,001–£250,000: 7; £250,001–£300,000: 4; £300,001–£350,000: 3; £450,001–£500,000: 1)
- Has a trading subsidiary
Self-declared on the annual return for the financial year ending 31/03/2024
- Government income: £7,776,865 — grants £7,776,865 (76); 3% of the £231,227,374 total gross income on the same return
- Employees paid over £60,000: 257 (£60,001–£70,000: 85; £70,001–£80,000: 39; £80,001–£90,000: 38; £90,001–£100,000: 31; £100,001–£110,000: 9; £110,001–£120,000: 11; £120,001–£130,000: 5; £130,001–£140,000: 5; £140,001–£150,000: 5; £150,001–£200,000: 17; £200,001–£250,000: 6; £250,001–£300,000: 4; £450,001–£500,000: 2)
- Has a trading subsidiary
Self-declared on the annual return for the financial year ending 31/03/2023
- Government income: £268,000 — grants £268,000 (1); under 1% of the £213,189,000 total gross income on the same return
- Employees paid over £60,000: 222 (£60,001–£70,000: 66; £70,001–£80,000: 38; £80,001–£90,000: 33; £90,001–£100,000: 20; £100,001–£110,000: 15; £110,001–£120,000: 8; £120,001–£130,000: 4; £130,001–£140,000: 6; £140,001–£150,000: 6; £150,001–£200,000: 14; £200,001–£250,000: 8; £250,001–£300,000: 2; £350,001–£400,000: 1; £400,001–£450,000: 1)
- Has a trading subsidiary
Corporate structure
- Registered company of the charity Companies House 06885462
- Trading subsidiary: FRANCIS CRICK TRADING LIMITED Companies House 10792548
- Turnover: £15.5m
- Profit before tax: £-1k
- Donated/gift-aided to the charity: £753k
“An adjusted qualifying charitable gift aid donation in relation to prior year reserves in 2024-25 of £600k (2024: £807k) was distributed to the parent company, Francis Crick Institute Limited in December 2024. In addition, charitable gift aid for the year 2024-25 of £153k to the parent company was provided for in statement of income and retained earnings.”
Company officers (Companies House)
- GEORGE, Peter Lutz on trustee list
- MCKERNAN, Ruth Mitchell, Dr on trustee list
- MITCHELL, Michelle Elizabeth on trustee list
- LORD, Graham Michael, Professor not on trustee list
- RØTTINGEN, John-Arne, Dr not on trustee list
- CHINNERY, Patrick Francis, Professor on trustee list
- RYAN, Mary Patricia, Professor on trustee list
- BIRD, Adrian Peter, Sir on trustee list
- EALET, Isabelle Marie on trustee list
- PANGALOS, Menelas Nicolas, Dr on trustee list
- GILVARY, Brian, Dr on trustee list
- BROWNE, Edmund John Phillip, Lord on trustee list
- SAXENA, Rahul Erik
Property (HM Land Registry)
Structured financials (annual return, FY ending 31/03/2025)
Trustees
- Lord Edmund John Phillip Brownechair
- Dr Brian Gilvary
- Dr John-Arne Rottingen
- Dr Menelas Nicolas Pangalos
- Dr Ruth Mitchell McKernan
- Isabelle Ealet
- Michelle Elizabeth Mitchell
- Peter Lutz George
- Professor Geraint Ellis Rees
- Professor Graham Michael Lord
- Professor Mary Patricia Ryan
- Professor Patrick Francis Chinnery
- Professor Sir Adrian Peter Bird
Income and spending
| Financial year end | Income | Spending |
|---|---|---|
| 31/03/2025 | £246.2m | £254.9m |
| 31/03/2024 | £231.2m | £237.6m |
| 31/03/2023 | £213.2m | £210.3m |
| 31/03/2022 | £185.6m | £197.4m |
| 31/03/2021 | £174.9m | £188.0m |
Common questions
Is THE FRANCIS CRICK INSTITUTE LIMITED financially healthy?
Per its FY2025 accounts: The accounts state that the charity reported a net deficit of £8.6m for the year ended 31 March 2025, driven by a £17.2m increase in expenditure that outpaced a £15.0m rise in income. Despite this operational loss, the charity maintains total reserves of £66.3m, which significantly exceed its stated policy target of £35m, providing a buffer against inflationary pressures. The trustees confirm that the charity has adequate resources to continue in operational existence for the foreseeable future. Its FY2025 accounts were audited by BDO LLP.
Who funds THE FRANCIS CRICK INSTITUTE LIMITED?
Funders whose own accounts filings name THE FRANCIS CRICK INSTITUTE LIMITED as a grant recipient include WELLCOME TRUST, BRITISH HEART FOUNDATION, THE CHRIS BANTON FOUNDATION, Blood Cancer UK Research, THE ALDAMA FOUNDATION.
Known funders
| Funder | Year | Amount | Purpose (as stated by the funder) |
|---|---|---|---|
| WELLCOME TRUST | FY2022 | £142.6m | |
| WELLCOME TRUST | FY2021 | £19.3m | Science |
| BRITISH HEART FOUNDATION | FY2025 | £3.2m | Research |
| THE CHRIS BANTON FOUNDATION | FY2024 | Unverified read£2.5m | |
| THE CHRIS BANTON FOUNDATION | FY2023 | £2.5m | |
| BRITISH HEART FOUNDATION | FY2021 | £700k | Research |
| THE CHRIS BANTON FOUNDATION | FY2025 | Unverified read£500k | |
| Blood Cancer UK Research | FY2022 | £379k | Research |
| THE ALDAMA FOUNDATION | FY2024 | £325k | Advancement of health or the saving of lives |
| THE STONEYGATE TRUST | FY2024 | £318k | |
| PANCREATIC CANCER UK | FY2026 | £297k | Exploring the role of the peripheral nervous system in pancreatic cancer risk |
| THE LISTER INSTITUTE OF PREVENTIVE MEDICINE | FY2021 | £250k | Lister Prize Fellowship for Dr James Lee |
| THE ALDAMA FOUNDATION | FY2022 | £240k | Advancement of health or the saving of lives |
| THE LORNA AND YUTI CHERNAJOVSKY BIOMEDICAL RESEARCH FOUNDATION | FY2026 | £238k | PhD studentship |
| THE ROYAL SOCIETY OF LONDON FOR IMPROVING NATURAL KNOWLEDGE (COMMONLY KNOWN AS THE ROYAL SOCIETY) | FY2023 | £188k | Grants to institutions |
| THE M AND L CHARITABLE TRUST | FY2025 | £180k | |
| ROSETREES | FY2023 | £130k | |
| THE WOOSNAM FOUNDATION | FY2022 | £120k | |
| THE HOBSON CHARITY LIMITED | FY2025 | £100k | Medical |
| PROSTATE CANCER RESEARCH | FY2022 | £86k | Targeting Wnt Signalling |
| THE NINEVEH CHARITABLE TRUST | FY2022 | £80k | |
| THE ROYAL SOCIETY OF LONDON FOR IMPROVING NATURAL KNOWLEDGE (COMMONLY KNOWN AS THE ROYAL SOCIETY) | FY2021 | £53k | University Research Fellowships |
| THE WOOSNAM FOUNDATION | FY2023 | Unverified read£50k | The advancement of research and education |
| Vivensa Foundation | FY2022 | £49k | Heterogeneity of Plasma Cells and of its Survival Niche in the context of Ageing |
| PROSTATE CANCER RESEARCH | FY2023 | £48k | PTEN and TSGs |
| THE STONEYGATE TRUST | FY2023 | £32k | |
| THE STONEYGATE TRUST | FY2025 | £21k | |
| THE HARRISON-FRANK FAMILY FOUNDATION (UK) LIMITED | FY2024 | £20k | |
| THE HARRISON-FRANK FAMILY FOUNDATION (UK) LIMITED | FY2025 | £20k | |
| THE JORON CHARITABLE TRUST | FY2021 | £20k | Dedicated to understanding the fundamental biology underlying health & disease. To translate discoveries into new ways to prevent, diagnose & treat illnesses. |
| THE COMPANY OF BIOLOGISTS | FY2025 | £15k | Multiple grants (see Note 7 detail) |
| MEDICAL RESEARCH FOUNDATION | FY2025 | £12k | Third Developmental Biology Symposium |
| THE COMPANY OF BIOLOGISTS | FY2023 | £11k | Other grants |
| THE BRITISH SOCIETY FOR HAEMATOLOGY | FY2025 | £10k | Research grants |
| MEDICAL RESEARCH FOUNDATION | FY2025 | £9k | Crick summer student training programme |
| MEDICAL RESEARCH FOUNDATION | FY2025 | £9k | Collaboration with Professor Carlos Estella to develop genetic tools in cell proliferation and cell death |
| Adelphi Genetics Forum | FY2025 | £1k | HAAM Summer School 2025 - virtual |
| WELLCOME TRUST | FY2025 | Unverified read£19 | Wellcome Leap |
| WELLCOME TRUST | FY2025 | Unverified read£19 | Discovery Research |
| THE STONEYGATE TRUST | FY2021 | amount not stated | |
| ROSETREES | FY2024 | amount not stated |
Government & lottery funding
| Funder | Date | Amount | Purpose |
|---|---|---|---|
| UK government | 21/12/2023 | £25k | Establishing The Immune Potential Of Enteric Glial Cells |
| UK government | 06/09/2023 | £127k | : Next-generation models and genetic therapies for rare neuromuscular diseases |
| UK government | 14/08/2023 | £75k | The metabolism of breast cancer metastasis to the lung: Key pathways and their implications in the metastatic microenvironment. |
| UK government | 04/05/2023 | £39k | Open Access Block Award 2023 - The Francis Crick Institute |
| UK government | 27/04/2023 | £272k | Biological validation of human liver somatic mutations |
| UK government | 04/04/2023 | £131k | GastruloGO: From gastruloid to gonadoid: exploring germ cell development in an embryo-like system |
| UK government | 10/03/2023 | £675k | Developing a rule book for rational discovery of molecular glues for intractable targets |
| UK government | 31/01/2023 | £97k | Network mechanisms underlying multisensory spatial attention |
| UK government | 12/12/2022 | £237k | The Role of Serotonin in the Modulation of Multisensory Spatial Attention |
| UK government | 27/09/2022 | £263k | SIGMA: Small molecule Inhibitors targeting the Genetic determinants of Mutagenesis and Adaptability in Mycobacterium tuberculosis |
| UK government | 08/09/2022 | £51k | Multidimensional investigation of cellular dynamics and lineage relationships in the vertebrate neural tube |
| UK government | 06/09/2022 | £138k | Discovery of High-level Antibiotic Resistance Mechanisms in Nature. |
| UK government | 23/08/2022 | £385k | Chromosome end protection in stem cells and development |
| UK government | 22/08/2022 | £345k | WIME: WNT-mediated immune evasion in intestinal homeostasis, regeneration and cancer |
| UK government | 12/08/2022 | £102k | ImmuneMetTx |
| UK government | 04/07/2022 | £259k | CRYPTOEXPORT: Exploring virulence and effector export in the intestinal parasite Cryptosporidium |
| UK government | 04/07/2022 | £259k | MultiSensDepthPercep: Midbrain Circuits Underlying Multisensory Depth Perception |
| UK government | 04/07/2022 | £259k | CancerNeuroscience: Systematic dissection of the crosstalk between cancer and the nervous system |
| UK government | 04/07/2022 | £259k | FoldingMap: Resolving Protein Biogenesis Pathways |
| UK government | 29/06/2022 | £163k | Impact of Ageing on Humoral Immune Protection from Infection |
| UK government | 25/05/2022 | £244k | Biophysical and Structural Analysis of Recombination Repair Proteins |
| UK government | 25/04/2022 | £340k | A Nanopathology Platform for Prediction and Early Detection of Disease in Kidney Transplant Rejection |
| UK government | 11/04/2022 | £214k | Crosstalk Between Tumour and Draining Lymph Nodes and its Impact on Triple-Negative Breast Cancer |
| UK government | 16/03/2022 | £497k | MRC IAA 2021 The Francis Crick Institute |
| UK government | 04/02/2022 | £595k | Integration of functional and structural knowledge across scales to decipher information processing in the mammalian brain |
Funders of similar charities
| Funder | Similar charities funded | Amount to them |
|---|---|---|
| DENISE COATES FOUNDATION | 1 | £6.2m |
| THE MASTER CHARITABLE TRUST | 1 | £1.3m |
| THE BILLMEIR CHARITABLE TRUST | 1 | £65k |
| B E M B RESEARCH AND EDUCATION TRUST | 1 | £44k |
| EDWARD HOLT TRUST | 1 | £40k |
| THE GRAND LODGE OF MARK MASTER MASONS' FUND OF BENEVOLENCE | 1 | £29k |
| KESWICK TO BARROW WALK | 1 | £24k |
| THE PHILIP OPPENHEIMER FOUNDATION | 1 | £20k |
Charities like this
- THE CHRISTIE CHARITY
- THE INSTITUTE FOR CANCER VACCINES AND IMMUNOTHERAPY
- THE CHRONIC DISEASE RESEARCH FOUNDATION
- FOUNDATION FOR THE SOCIOLOGY OF HEALTH AND ILLNESS
- SCIENCE PROJECTS
- THE INTENSIVE CARE SOCIETY
Side by side with its peers
| Charity | Income | Top pay band | Staff >£60k | Reserves vs policy | Fundraising cost | Going concern |
|---|---|---|---|---|---|---|
| THE FRANCIS CRICK INSTITUTE LIMITED | £246.2m | — | — | above | — | no doubt |
| THE CHRISTIE CHARITY | £23.8m | — | — | unclear | 17.0% | no doubt |
| THE INSTITUTE FOR CANCER VACCINES AND IMMUNOTHERAPY | £433k | £70,001 - £80,000 | 1 | unclear | 6.0% | no doubt |
| THE CHRONIC DISEASE RESEARCH FOUNDATION | £214k | — | 0 | above | — | no doubt |
| FOUNDATION FOR THE SOCIOLOGY OF HEALTH AND ILLNESS | £371k | — | 0 | above | — | no doubt |
| SCIENCE PROJECTS | £1.2m | — | — | unclear | — | no doubt |