GENOME RESEARCH LIMITED

Registered charity 1021457 · accounts filings on the Charity Commission register · Wikidata: Q1142544 · Wikipedia · also known as WELLCOME TRUST SANGER INSTITUTE

A) TO ADVANCE RESEARCH INTO AND INVESTIGATION OF THE HUMAN GENOME AND TO PUBLISH THE USEFUL RESULTS OF SUCH RESEARCH B) TO ADVANCE SCIENTIFIC AND MEDICAL RESEARCH

Objects

A) TO ADVANCE RESEARCH INTO AND INVESTIGATION OF THE HUMAN GENOME AND TO PUBLISH THE USEFUL RESULTS OF SUCH RESEARCH B) TO ADVANCE SCIENTIFIC AND MEDICAL RESEARCH

Area of benefit: NOT DEFINED

The charity’s charitable objects and area of benefit, quoted from its governing document as held on the Charity Commission register.

Causes: Education/training · The Advancement Of Health Or Saving Of Lives · website · Get email alerts

Registered contact address: South Cambridgeshire, East of England, England (from the postcode on the register)

Latest income
£180.3m
Latest spending
£183.5m
Registered
1993
Accounts read
FY2025

Financial health, per its FY2025 accounts

The accounts state that the charity reported total income of £180.3 million and total expenditure of £183.5 million, resulting in a net expenditure of £2.7 million for the year. However, total net assets increased to £273.7 million, largely driven by a significant pension surplus of £108.2 million and other recognised gains. The trustees confirm that the charity is in a strong financial position with sufficient unrestricted reserves and ongoing funding support from its parent, Wellcome, to continue as a going concern.

Automated summary of the FY2025 accounts; the evidenced findings below carry the verbatim passages.

What the accounts disclose

Highest-paid employee band: £290,000 to £299,999 — in the top quarter for charities its size (median £184k)
“£290,000 to £299,999 1 1”
Per its FY2025 accounts as filed with the Charity Commission.
Largest income source: Wellcome Trust (74% of income)
“Income for the year totalled £180.3 million (2024: £177.3 million) of which 74% (2024: 72%) was provided by Wellcome.”
Per its FY2025 accounts as filed with the Charity Commission.
Trading subsidiary: Genome Research Trading Limited, GRL Construction Limited, Base RX Limited
“As at 30 September 2025, Genome Research Trading Limited, GRL Construction Limited and Base RX Limited were 100% subsidiaries of GRL.”
Per its FY2025 accounts as filed with the Charity Commission.

Accounts audited by Deloitte LLP. Discloses 4 of 6 completeness components.

Year-over-year changes

Comparing this charity’s FY2024 and FY2025 accounts as analysed by this site.

Policies the charity declares

In its annual return the charity told the Commission that it has the policies listed below. This is self-declared: it is not verified by the Commission or by this site, and it is not evidence of how a policy works in practice.

From the charity’s annual return (Part A, self-declared)

Answers and figures the charity gave in Part A of its annual return to the Charity Commission. They are self-declared: not verified by the Commission or by this site. Only positive answers and figures are listed; items not listed are simply not shown.

Self-declared on the annual return for the financial year ending 30/09/2025

  • Government income: £2,015,983 — grants £2,015,983 (16); 1% of the £180,349,000 total gross income on the same return
  • Employees paid over £60,000: 284 (£60,001–£70,000: 136; £70,001–£80,000: 60; £80,001–£90,000: 27; £90,001–£100,000: 16; £100,001–£110,000: 14; £110,001–£120,000: 8; £120,001–£130,000: 3; £130,001–£140,000: 6; £140,001–£150,000: 1; £150,001–£200,000: 11; £250,001–£300,000: 2)
  • Trustee benefits, answered Yes to: any trustee benefit; payments to trustees for services to the charity
  • Has a trading subsidiary

Self-declared on the annual return for the financial year ending 30/09/2024

  • Government income: £1,666,214 — grants £1,666,214 (15); under 1% of the £177,347,000 total gross income on the same return
  • Employees paid over £60,000: 298 (£60,001–£70,000: 143; £70,001–£80,000: 67; £80,001–£90,000: 26; £90,001–£100,000: 16; £100,001–£110,000: 13; £110,001–£120,000: 10; £120,001–£130,000: 3; £130,001–£140,000: 5; £140,001–£150,000: 2; £150,001–£200,000: 10; £250,001–£300,000: 3)
  • Trustee benefits, answered Yes to: any trustee benefit; payments to trustees for services to the charity
  • Has a trading subsidiary

Self-declared on the annual return for the financial year ending 30/09/2023

  • Government income: £21,732,222 — contracts £20,666,557 (1), grants £1,065,665 (24); 11% of the £189,031,000 total gross income on the same return
  • Employees paid over £60,000: 240 (£60,001–£70,000: 119; £70,001–£80,000: 41; £80,001–£90,000: 25; £90,001–£100,000: 19; £100,001–£110,000: 11; £110,001–£120,000: 4; £120,001–£130,000: 4; £130,001–£140,000: 3; £150,001–£200,000: 9; £200,001–£250,000: 3; £250,001–£300,000: 1; £350,001–£400,000: 1)
  • Trustee benefits, answered Yes to: any trustee benefit; payments to trustees for services to the charity
  • Has a trading subsidiary

Source: this charity’s annual returns on the Charity Commission register.

In the news

Recent coverage mentioning this charity by name (automated match; headlines belong to their publishers).

Funders the charity credits

Named as funders/supporters on the charity’s own website (the charity’s claim, distinct from accounts-verified grants).

UK research funding (UKRI Gateway to Research)

Property (HM Land Registry)

1 registered title in England and Wales held by the charity’s company or corporate body (0 freehold). All charity-held property. Contains HM Land Registry data © Crown copyright, OGL v3.0.

Public profiles (found on the charity’s own website): facebook (10,375 likes)

Structured financials (annual return, FY ending 30/09/2025)

Total income
£180.3m
Total spending
£183.5m
Reserves (reported)
£32.0m
Employees
1,301

Reported reserves equal ~2.1 months of spending — below the median for charities its size (median 2.6 months; benchmarks).

Per its annual return, largest income source: Charitable activities (91% of income) — components as reported reconcile to the return’s total income; not from the accounts narrative.

Per its annual return, cost of raising funds: 0.0% of total income — below the median for charities its size (3.2%) (benchmarks).

Trustees · trustee networks

Trustee list from the Charity Commission register (current, not historical).

Operates in: Cambridgeshire

Income and spending

Financial year endIncomeSpending
30/09/2025£180.3m£183.5m
30/09/2024£177.3m£183.5m
30/09/2023£189.0m£184.0m
30/09/2022£185.9m£183.2m
30/09/2021£221.5m£207.9m

Common questions

Is GENOME RESEARCH LIMITED financially healthy?

Per its FY2025 accounts: The accounts state that the charity reported total income of £180.3 million and total expenditure of £183.5 million, resulting in a net expenditure of £2.7 million for the year. However, total net assets increased to £273.7 million, largely driven by a significant pension surplus of £108.2 million and other recognised gains. The trustees confirm that the charity is in a strong financial position with sufficient unrestricted reserves and ongoing funding support from its parent, Wellcome, to continue as a going concern. Its FY2025 accounts were audited by Deloitte LLP.

What does the highest-paid employee of GENOME RESEARCH LIMITED earn?

Per its FY2025 accounts, the highest-paid employee was in the £290,000 to £299,999 band.

Who funds GENOME RESEARCH LIMITED?

Funders whose own accounts filings name GENOME RESEARCH LIMITED as a grant recipient include HEALTH DATA RESEARCH UK, THE KENNEL CLUB CHARITABLE TRUST.

Known funders

Grants to this charity found in funders’ own accounts filings.

FunderYearAmountPurpose (as stated by the funder)
HEALTH DATA RESEARCH UKFY2023£2.2mHDR UK Cambridge Substantive Site
ALZHEIMER'S RESEARCH UKFY2025Unverified read£69k
THE KENNEL CLUB CHARITABLE TRUSTFY2024£65kEducation and other grants
THE KENNEL CLUB CHARITABLE TRUSTFY2023£40kEducation and other grants
THE KENNEL CLUB CHARITABLE TRUSTFY2022£15kEducation and other grants

Grants marked “Unverified read” were flagged by automated checks as possibly misread from the funder’s filed accounts. They are listed, but left out of the totals, counts and funder relationships this site computes.

Government & lottery funding

Grants to this charity published as open data by government and lottery funders (360Giving).

FunderDateAmountPurpose
UK government—£24kIdentification and curation of proteins and pathways involved in immune system regulation
UK government—£24kNext Generation sequencing of barcoded plasmodium falciparum mutants to dissect parasite fitness costs associated with drug resistance
UK government—£59kWormbase ParaSite
UK government—£83kPredicting cell-cell horizontal transmission of antibiotics resistance from genome and phenome
UK government—£87kDeciphering the effects of genetic variability in regulatory T cells - links with autoimmunity
UK government—£109kJPND Genomic Instability in Alzheimer's Disease and Related Disorders: a Single-Cell Approach
UK government—£130kPrevention and Restriction of Antimicrobial Resistance in Pneumococci by Multi-Level Modelling
UK government—£200kThe identification of genetic vulnerabilities in head and neck cancers for the development of novel therapies.

Funders of similar charities

Funders whose accounts show grants to charities similar to this one (and no recorded grant to this charity) — a starting list for fundraisers.

Charities like this

Semantically similar by activities and financial character, from our analysed corpus. Compare with CANCER RESEARCH AND GENETICS UK.

Side by side with its peers

CharityIncomeTop pay bandStaff >£60kReserves vs policyFundraising costGoing concern
GENOME RESEARCH LIMITED£180.3m£290,000 to £299,999—unclear—no doubt
CANCER RESEARCH AND GENETICS UK FY2025£128k—0unclear—no doubt
MEDICAL RESEARCH FOUNDATION FY2025£3.7m——unclear—no doubt
THE ASSOCIATION FOR CLINICAL GENOMIC SCIENCE FY2025£57k—0above—no doubt
SOCIETY OF GENEALOGISTS FY2025£768k——above—no doubt
THE GEN FOUNDATION FY2025£32k——unclear—no doubt

Each row is that charity’s latest analysed filing; every value is quote-backed on its own page.