GENOME RESEARCH LIMITED

Registered charity 1021457 · accounts filings on the Charity Commission register · also known as WELLCOME TRUST SANGER INSTITUTE

A) TO ADVANCE RESEARCH INTO AND INVESTIGATION OF THE HUMAN GENOME AND TO PUBLISH THE USEFUL RESULTS OF SUCH RESEARCH B) TO ADVANCE SCIENTIFIC AND MEDICAL RESEARCH

Causes: Education/training · The Advancement Of Health Or Saving Of Lives · website · Get email alerts

Latest income
£180.3m
Latest spending
£183.5m
Registered
1993
Accounts read
FY2025

Financial health, per its FY2025 accounts

The accounts state that total net assets increased to £273.7 million, supported by a pension surplus of £108.2 million and unrestricted income funds of £24.4 million. The charity reports net current assets of £36.2 million and confirms that core funding from Wellcome is sufficient to meet obligations for the foreseeable future. The trustees are satisfied that the going concern basis is appropriate, with no material uncertainties identified.

Automated summary of the FY2025 accounts; the evidenced findings below carry the verbatim passages.

What the accounts disclose

Largest income source: Wellcome Trust (74% of income)
“Income for the year totalled £180.3 million (2024: £177.3 million) of which 74% (2024: 72%) was provided by Wellcome.”
Per its FY2025 accounts as filed with the Charity Commission.
Payments to trustees: One Director received remuneration totalling £7,885 in respect of other positions held. Eight Directors received travel and accommodation expenses of £26,226.
“The Directors of GRL received no remuneration in relation to their duties as Directors, however one Director received remuneration totalling £7,885 (2024: £7,686) in respect of other positions held and eight Directors received travel and accommodation expenses of £26,226 (2024: £20,949).” — page 44
Per its FY2025 accounts as filed with the Charity Commission.
Related-party transaction: The Wellcome Trust provides an open-ended facility to exchange dollars at a favourable rate, resulting in a gain of £2.2 million.
“The Wellcome Trust provide the Company with an open-ended facility to exchange dollars at a favourable rate. The Company recognised a gain in relation to this arrangement in the year ended 30 September 2025 of £2.2 million (2024: £2.8 million).” — page 53
“The Wellcome Trust pay interest against the net intercompany balance owed to GRL. GRL received £1.6 million in the year ended 30 September 2025 (2024: £2.1 million) in relation to this arrangement.” — page 53
Per its FY2025 accounts as filed with the Charity Commission.
Related-party transaction: The Wellcome Trust pays interest against the net intercompany balance owed to GRL, amounting to £1.6 million.
“The Wellcome Trust provide the Company with an open-ended facility to exchange dollars at a favourable rate. The Company recognised a gain in relation to this arrangement in the year ended 30 September 2025 of £2.2 million (2024: £2.8 million).” — page 53
“The Wellcome Trust pay interest against the net intercompany balance owed to GRL. GRL received £1.6 million in the year ended 30 September 2025 (2024: £2.1 million) in relation to this arrangement.” — page 53
Per its FY2025 accounts as filed with the Charity Commission.
Trading subsidiary: Genome Research Trading Limited, GRL Construction Limited, Base RX Limited
“As at 30 September 2025, Genome Research Trading Limited, GRL Construction Limited and Base RX Limited were 100% subsidiaries of GRL.”
Per its FY2025 accounts as filed with the Charity Commission.

Accounts audited by Deloitte LLP. Discloses 3 of 6 completeness components.

In the news

Recent coverage mentioning this charity by name (automated match; headlines belong to their publishers).

Funders the charity credits

Named as funders/supporters on the charity’s own website (the charity’s claim, distinct from accounts-verified grants).

UK research funding (UKRI Gateway to Research)

Property (HM Land Registry)

1 registered title in England and Wales held by the charity’s company or corporate body (0 freehold). All charity-held property. Contains HM Land Registry data © Crown copyright, OGL v3.0.

Public profiles (found on the charity’s own website): facebook (10,375 likes)

Structured financials (annual return, FY ending 30/09/2025)

Total income
£180.3m
Total spending
£183.5m
Reserves (reported)
£32.0m
Employees
1,301

Reported reserves equal ~2.1 months of spending — below the median for charities its size (median 2.7 months; benchmarks).

Per its annual return, largest income source: Charitable activities (91% of income) — components as reported reconcile to the return’s total income; not from the accounts narrative.

Per its annual return, cost of raising funds: 0.0% of total income — below the median for charities its size (2.9%) (benchmarks).

Trustees · trustee networks

Trustee list from the Charity Commission register (current, not historical).

Operates in: Cambridgeshire

Income and spending

Financial year endIncomeSpending
30/09/2025£180.3m£183.5m
30/09/2024£177.3m£183.5m
30/09/2023£189.0m£184.0m
30/09/2022£185.9m£183.2m
30/09/2021£221.5m£207.9m

Common questions

Is GENOME RESEARCH LIMITED financially healthy?

Per its FY2025 accounts: The accounts state that total net assets increased to £273.7 million, supported by a pension surplus of £108.2 million and unrestricted income funds of £24.4 million. The charity reports net current assets of £36.2 million and confirms that core funding from Wellcome is sufficient to meet obligations for the foreseeable future. The trustees are satisfied that the going concern basis is appropriate, with no material uncertainties identified. Its FY2025 accounts were audited by Deloitte LLP.

Who funds GENOME RESEARCH LIMITED?

Funders whose own accounts filings name GENOME RESEARCH LIMITED as a grant recipient include HEALTH DATA RESEARCH UK, ALZHEIMER'S RESEARCH UK, THE KENNEL CLUB CHARITABLE TRUST.

Known funders

Grants to this charity found in funders’ own accounts filings.

FunderYearAmountPurpose (as stated by the funder)
HEALTH DATA RESEARCH UKFY2023£2.2mHDR UK Cambridge Substantive Site
ALZHEIMER'S RESEARCH UKFY2025£69k
THE KENNEL CLUB CHARITABLE TRUSTFY2024£65kEducation and other grants
THE KENNEL CLUB CHARITABLE TRUSTFY2023£40kEducation and other grants
THE KENNEL CLUB CHARITABLE TRUSTFY2022£15kEducation and other grants

Government & lottery funding

Grants to this charity published as open data by government and lottery funders (360Giving).

FunderDateAmountPurpose
UK government—£24kIdentification and curation of proteins and pathways involved in immune system regulation
UK government—£24kNext Generation sequencing of barcoded plasmodium falciparum mutants to dissect parasite fitness costs associated with drug resistance
UK government—£59kWormbase ParaSite
UK government—£83kPredicting cell-cell horizontal transmission of antibiotics resistance from genome and phenome
UK government—£87kDeciphering the effects of genetic variability in regulatory T cells - links with autoimmunity
UK government—£109kJPND Genomic Instability in Alzheimer's Disease and Related Disorders: a Single-Cell Approach
UK government—£130kPrevention and Restriction of Antimicrobial Resistance in Pneumococci by Multi-Level Modelling
UK government—£200kThe identification of genetic vulnerabilities in head and neck cancers for the development of novel therapies.

Funders of similar charities

Funders whose accounts show grants to charities similar to this one (and no recorded grant to this charity) — a starting list for fundraisers.

Charities like this

Semantically similar by activities and financial character, from our analysed corpus. Compare with GENESIS AMERICA (UK) LIMITED.

Side by side with its peers

CharityIncomeTop pay bandStaff >£60kReserves vs policyFundraising costGoing concern
GENOME RESEARCH LIMITED£180.3m——unclear—no doubt
GENESIS AMERICA (UK) LIMITED FY2025£1.1m—0unclear—no doubt
UK BIOBANK LIMITED FY2025£68.9m£270,001 - £280,000—within—no doubt
STRUCTURAL GENOMICS CONSORTIUM FY2025£4.7m—0unclear—no doubt
GENESIS RESEARCH TRUST FY2025£524k—0unclear—no doubt
THE LORNA AND YUTI CHERNAJOVSKY BIOMEDICAL RESEARCH FOUNDATION FY2025£508k—0above—no doubt

Each row is that charity’s latest analysed filing; every value is quote-backed on its own page.